Project Description

ClickGene offers 14 Early Stage Researchers (ESRs) the opportunity to develop and learn skills that are required by next-generation research leaders in biopharmaceutical, nanotechnology, biodiagnostic and related industries. The ITN funded by the European Commission under the Horizon 2020 programme will link directly into COST Action CM1201 (Biomimetic Radical Chemistry) with young innovative talents for networking and training purposes. Thanks to transferable skills training, intersectorial and cross-disciplinary secondments, and industry targeted workshops, the education of biomaterials chemists with expertise in click-chemistry and cutting edge application areas of gene therapy, nanotechnology and biological diagnostics will be achieved by the ClickGene project.

Abstract

Gene therapy is expected to play a key role in next-generation medicine by correcting the underlying genetic causes of disease, thereby facilitating personalised medicine. Current gene therapy methods possess undesirable side effects, including insertional mutagenesis, toxicity, low efficiency and off-target cutting. Questions also remain regarding the optimal methods for delivering nucleases into cells and tissues. These limitations will be addressed through the original and innovative approach of the ClickGene network.
ClickGene’s research objectives are to train 14 ESRs in the field of biomaterials development with specific focus on, i.) siteselective genetic engineering, ii.) liposomal nanoparticle drug delivery, and iii.) optogenetic diagnostic probes for epigenetic base detection.
The training provided will match the skills required by next-generation research leaders in biopharmaceutical, nanotechnology, biodiagnostic and other industries. Allied to academic strength in this network, ClickGene features highly competitive industry partners with expertise in commercialisation of nucleic acid click-chemistry (baseclick, ATDBio) and liposomal and lipidome technology (LipiNutraGen). Thus, synergy between both commercial and academic partners will enable ESRs to develop gene-targeted technology within a highly productive, engaging, and exciting training network.

 

Our Role

accelopment is a Partner Organisation in ClickGene. We are involved in three areas of the project – assisting in project management tasks, coordinating the communication and dissemination activities and contributing to the ESR training activities with a Grant writing course.

Project Details

Coordinator: 
Dublin City University, IE
Partners: 
ATDbio Ltd, UK
baseclick GmbH, DE
Institute of Organic Chemistry and Biochemistry ASCR, CZ
LipiNutraGen srl, IT
Ludwig Maximilian University Munich, DE
National Center for Scientific Research “Demokritos”, GR
National Research Council, IT
Oxford University, UK
accelopment AG, CH (Partner Organisation)
Contact: 
Duration: 
01.01.2015 - 31.12.2018
Budget: 
3.7 million euro
Our Services: 
Proposal Writing
Contract Negotiations
Project Management
Project Dissemination
Funding Programme: 
  • H2020-MSCA-ITN-2014 (ETN)
Area: 
Chemistry

Testimonial

Dr Andrew Kellett, Dublin City University, IE

"accelopment challenged us, as scientists, to identify why our idea really mattered and demanded fine detail in every aspect of our proposal. It is in these margins that success can be achieved."

Prof Andrew Kellett, Dublin City University, IE