Project Description

The MUSIQ project is an innovative research and training network funded under the Horizon 2020 Marie Skłodowska-Curie Actions. 15 Early Stage Researchers (ESRs) will work toward the ambitious goal of developing the next-generation optical microscopy exploiting quantum coherent nonlinear phenomena. The MUSIQ network brings together a unique team at the forefront of optical microscopy and ultrafast laser technology developments merged with fundamental understanding of coherent light-matter interaction phenomena, development of quantitative image analysis tools, and biomedical/pharmaceutical real-world applications.


The MUSIQ network will investigate nonlinear optical phenomena originating from the intrinsic response of natural biomolecules to achieve label-free imaging and overcome artefacts from sample staining/fluorescence methods. Furthermore, the project aims to combine nonlinear (i.e. multiphoton) imaging with ultrafast two-dimensional spectroscopy to increase specificity and unravel quantum coherences in biomolecules and to achieve single molecule detection and super-resolution in coherent nonlinear imaging via a combination of approaches, including the enhancement of the light field in the vicinity of metallic (plasmonic) nanostructures.

The overarching training objective of MUSIQ is to create the next generation of creative, innovative, well-connected scientists in this technologically demanding forefront field, by implementing a multidisciplinary intersectoral training and research programme at the interface between physics, chemistry and life sciences. MUSIQ will enhance the career perspective of the recruited ESRs by training them in a broad range of scientific, technical and transferable skills, through a unique combination of projects, secondments, and tailored courses.

Project Details

Cardiff University, UK
accelopment AG, CH
Cardiff University, UK
Politecnico di Milano, IT
Centre National de la Recherche Scientifique, FR
Fundacio Institut de Ciencies Fotoniques, ES
Universität Konstanz, DE
Università degli Studi di Modena e Reggio Emilia, IT
GlaxoSmithKline Research and Development Ltd., UK
Leica Microsystems CMS GmbH, DE
MGF Šviesos konversija, UAB (Light Conversion), LT
Scientific Volume Imaging BV, NL
Scientific Volume Imaging BV, NL
Science Made Simple Ltd., UK
VENETON Laser Technologies GmbH, DE
A.P.E. Angewandte Physik und Elektronik GmbH, DE
Prof Paola Borri
01.04.2019 – 31.03.2023
3.9 million euro
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Funding Programme: 
  • H2020-MSCA-ITN
  • Chemistry
  • Lifesciences