Testimonial accelopment challenged us, as scientists, to identify why our idea really mattered and required fine detail in every aspect of our proposal. It is in these margins that success can be achieved.
Prof. Dr. Andrew Kellett
ClickGene & NATURE-ETN Project Coordinator
Dublin City University, Ireland

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Polynuclear Platinum (II) Biomaterials for Antisense Therapeutic Application and Detection of Human Genetic Disease

Gene therapy is emerging as an effective personalised treatment with vast clinical application against cancer, cardiovascular, infectious, neurological, inflammatory, genetic, and many other human diseases. A key enabler of gene therapy is antisense drug discovery. Antisense therapeutics are biologic in nature and specifically target protein production at the transcriptional or translational level. The PPtBio research project will develop a breakthrough class of targeted antisense therapeutics and diagnostic hybridisation probes that address current limitations within oligonucleotide biomaterials.

The overarching aim of the PPtBio project is to develop new 21st century drugs for antisense gene therapy and diagnostics in human health. These proposed synthetic agents will be investigated for their targeted genetic potential and constitute an exciting, break-through, class of biomaterial with significant future development potential that will underpin competitiveness of industry and enterprise within Ireland.
PPtBio will also empower an innovative and enterprising economy by providing high-level training in biomaterials science, gene therapy, genetic disease detection, and molecular biology. Each of these training components will be directly influenced by the proposed industry-academia partnership with ATDBio Ltd., and will lead to future employment for project researchers in high-value cutting edge jobs within Ireland. Solving major national and global challenges in healthcare are key drivers in Ireland’s strategy for funding health-associated research.
The PPtBio project will add directly, and help shape the future healthcare of Ireland by developing smart materials that can detect disease at the genetic level and help treat specific disease classes using antisense therapy. Hence, PPtBio will contribute to effective personalised healthcare.

Dr Andrew Kellett


AreaLife Sciences
Duration01.01.2017 – 31.12.2020
Budget3.6 million euro


We have more than 25 years of experience in FP7, Horizon 2020 and other funding programmes, from finding the best funding scheme, to proposal writing, project management and communication. accelopment has the expertise and the staff to support you from the inception of your research and innovative idea to the management of your funded project. We will be your sparring partner through all the steps including choosing the right call and funding scheme, proposal writing, the negotiation of your grant with the European Commission (EC), and maximising the impact of your R&D project. We also like to share our experience and offer several targetted training options.t for the boxes



Being able to support intrinsically motivated researchers and innovative companies in shaping our future while contributing to their career and business development is both fulfilling and challenging.

Dr. Jeanette Müller