Horizon Europe’s 2025 draft Cluster 4 Digital, Industry, and Space – any call topic of interest to you?
20th March 2025 at 3:19 pm
Horizon Europe promotes research and innovation for a competitive, digital and sustainable future. Advancements in digital technologies are reshaping every sector of the economy and society. Horizon Europe provides researchers and innovators with the resources to build a resilient, green and digital Europe. With a total budget of 1.4 billion euros in the 2025 draft Work Programme, Cluster 4 will support initiatives in advanced manufacturing, AI, robotics, space, circular and low-carbon industries, as well as emerging technologies like quantum computing and big data.
Unlocking the future – insights into the 2025 draft Work Programme for Cluster 4
The 2025 draft of the Digital, Industry, and Space Work Programme has been published, giving you an early opportunity to plan resources and form consortia for future submissions. While the draft is still subject to revisions, assessing it now will provide crucial insights, allowing you to prepare competitive proposals ahead of the official call deadlines strategically. As shown here, the 2025 draft Work Programme is structured around six key Destinations that drive sustainability and digital innovation. Many call topics are backed up by European Partnerships in digital, industry and space such as Made in Europe, Processes4Planet, Clean Steel, Virtual Worlds, Photonics and AI/Data/Robotics.
Horizon Europe initiatives for digital, industry and space – our team helps you turn your ideas into projects
At accelopment, we have extensive experience in securing EU funding for research and innovation projects, with a strong track record in Horizon Europe digital and industry projects. Our team of experts supports researchers, companies and institutions throughout the entire funding process – from strategic grant planning, to proposal writing, project management and communication and dissemination. With deep knowledge of funding opportunities, we help our partners maximise their chances of success in securing European research grants. We are currently involved in several significant digital-related projects, including CORENET, PEARL-DNA, PIONEAR, ROADVIEW and more, and look forward to supporting research institutions and companies in the upcoming calls.
Horizon Europe 2025 Cluster 4 call topics – key facts for you to know*
Get ready to uncover the most exciting funding opportunities for digital, industry, and space innovation in Horizon Europe! The tables below outline key calls by Destination, highlighting the EU’s investments in sustainable, digital and circular industries, strategic autonomy in critical technologies, and innovation in AI, space and data infrastructure. Whether chasing funding for advanced materials or tackling AI challenges, this is your go-to resource for the next big opportunity.
Destination 5: Open Strategic Autonomy in Developing, Deploying and Using Global Space- Based Infrastructure, Services, Applications and Data
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-2025-02-SPACE-11: CSA on access to European spaceports | CSA | 1 | Around 1 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-12: Digital solutions for autonomy for space transportation systems, design and simulation tools – Digital enablers and building blocks | RIA | 3 | 1 to 3 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-13: Digital solutions for autonomy for space transportation systems, design and simulation tools – targeting demonstration | IA | 7 | 4 to 7 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-21: ISOS Pilot Mission Detailed Design – Servicing component | RIA | 18 | 6 to 12 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-22: ISOS Pilot Mission Detailed Design – HOST component | RIA | 17.5 | 12 to 17.5 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-23: ISOS Pilot Mission Detailed Design – Logistics component | RIA | 12 | 10 to 12 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-24: ISOS Pilot Mission Detailed Design – satAPPS component | RIA | 5 | 2 to 3 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-31: Digital enablers and building blocks for Earth Observation and Satellite telecommunication for Space solutions | RIA | 6 | 1 to 5 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-32: Preparing demonstration missions for collaborative Earth Observation and Satellite telecommunication for Space solutions | IA | 11 | 2 to 6 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-41: Copernicus Climate Change Service (C3S) evolution: new and innovative processing and methods for future Sentinels and other satellites for reanalyses | RIA | 10 | Around 10.00 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-42: Copernicus Atmosphere Monitoring Service (CAMS) evolution: improved soil-vegetation-atmosphere modelling and data assimilation of atmospheric constituents | RIA | 3 | Around 3 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-43: Copernicus Anthropogenic CO₂ Emissions Monitoring & Verification Support (CO2MVS) capacity: new and innovative methods to estimate the impact of fires on vegetation and related carbon fluxes | RIA | 3 | Around 3 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-44: Copernicus Marine Environment Monitoring Service (CMEMS) evolution: new and innovative ocean data assimilation techniques | RIA | 5 | Around 5 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-45: Supporting the AI/ML digital transition of Copernicus Services | RIA | 12 | Around 12 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-46: Innovative Earth observation services in support of maritime litter detection and ship source pollution policies | IA | 5 | Around 5 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-71: Space Critical EEE Components and Related Technologies for EU non-dependence | RIA | 12 | 1 to 5 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-72: Space Critical Equipment and Related Technologies for EU non-dependence | RIA | 8 | 3 to 4 | 04/09/2025 |
| HORIZON-CL4-2025-02-SPACE-81: EU-Japan cooperation on the exploitation of Quantum Space Gravimetry data | RIA | 0.5 | 0.45 to 0.5 | 04/09/2025 |
Destination 1: Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01: Integrated approaches for remanufacturing (Made in Europe Partnership) (IA) | IA | 35 | 5 to 7 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02: Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA) | RIA | 35 | 4 to 6 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05: Advanced manufacturing technologies for leadership of EU manufacturers in products for the net-zero industry (Made in Europe Partnership) (IA) | IA | 42 | 5 to 7 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-11: Enhanced logistics and operations of construction sites (IA) | IA | 13 | Around 6.5 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-21: Demonstrators for clusters of social circular enterprises (IA) | IA | 10 | Around 5 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31: From heat-driven processes to the use of mechanical and electric forces (Processes4Planet Partnership) (IA) | IA | 25 | 8 to 10 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32: Green and resilient flexible production processes (Processes4Planet Partnership) (IA) | IA | 25 | 8 to 10 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33: Integrated use of renewable energy carriers in industrial sites (Processes4Planet Partnership) (RIA) | RIA | 25 | 6 to 8 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34: Smart integration of net-zero technologies into Energy Intensive Industries (Processes4Planet and Made in Europe Partnerships) (IA) | IA | 25 | 5 to 9 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-35: Developing and embedding upcycling technologies into viable business (Processes4Planet Partnership) (IA) | RIA | 28 | Around 14 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-36: Safe and clean processing technologies and products (Processes4Planet Partnership) (RIA) | IA | 48 | 8 to 12 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37: Solving issues in carbon-neutral iron and steel-making processes with diverse input materials of varying quality (Clean Steel Partnership) (RIA) | RIA | 24 | 6 to 8 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38: Synergies and mutual learning with national and regional initiatives in Europe on industrial decarbonisation (Processes4Planet and Clean Steel Partnerships) (CSA) | CSA | 2 | Around 2 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39: Towards human-centric, sustainable, and resilient energy-intensive industries (Processes4Planet and Clean Steel Partnerships) (CSA) | CSA | 2 | Around 2 | 23/09/2025 |
Destination 2: Achieving technological leadership for Europe’s open strategic autonomy in raw materials, chemicals and innovative materials
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61: Technologies for critical raw materials and strategic raw materials from end-of-life products (IA) | IA | 24 | Around 8 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62: Strategic Partnerships for Raw Materials: Innovative Approaches for sustainable production of Critical Raw Materials (IA) | IA | 30 | Around 7.5 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63: Innovative solutions for the sustainable production of Semiconductor raw materials (IA) | IA | 24 | Around 8 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64: EU Co-funded Partnership on raw materials for the green and digital transition (Programme Co-fund action) | COFUND | 45 | Around 90 (2025-2027) | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-42: Innovative Advanced Materials (IAMs) for product monitoring, smart maintenance, and repair strategies in the construction sector (RIA) (Innovative Advanced Materials for Europe partnership) | RIA | 30 | Around 6 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-43: Innovative Advanced Materials (IAMs) for robust, fast-curing sealants and coatings for manufacturing and final assembly (IA) (Innovative Advanced Materials for Europe partnership) | IA | 30 | Around 6 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44: Innovative Advanced Materials Innovation Procurement (CSA) | CSA | 2 | Around 2 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45: Materials Commons for Europe (IA) | IA | 20 | Around 20 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-51: Development of safe and sustainable by design alternatives to Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) (IA) | IA | 30 | Around 7 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52: Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA) | RIA | 15 | 4 to 5 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31: Digitally enabled local-for-local textile and apparel production (Textiles for the Future Partnership) (IA) | IA | 10 | Around 5 | 23/09/2025 |
Destination 4: Achieving open strategic autonomy in digital and emerging enabling technologies
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61: AI Foundation models in science (RIA) | RIA | 12 | 4 to 6 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62: Facilitated cooperation for AI in Science (CSA) | CSA | 3 | Around 3 | 23/09/2025 |
| HORIZON-CL4-2025-03-DIGITAL-EMERGING-01: Continuation of the Quantum Technologies Flagship (CSA) | CSA | 4.5 | Around 4.5 | 02/10/2025 |
| HORIZON-CL4-2025-03-DIGITAL-EMERGING-02: Quantum Computing – complementing the quantum computing FPAs with the development of a technology-agnostic software stack (RIA) | RIA | 10 | Around 5 | 02/10/2025 |
| HORIZON-CL4-2025-03-DIGITAL-EMERGING-03: International cooperation: joint research and development with the Republic of Korea (RIA) | RIA | 8 | 2.5 to 2.7 | 02/10/2025 |
| HORIZON-CL4-2025-03-DIGITAL-EMERGING-04: Post-exascale HPC (CSA) | CSA | 2.5 | Around 2.5 | 02/10/2025 |
| HORIZON-CL4-2025-03-DIGITAL-EMERGING-07: Robust and trustworthy Generative AI for Robotics and industrial automation (RIA) (AI/Data/Robotics & Made in Europe Partnerships) | RIA | 85 | Around 40 | 02/10/2025 |
| HORIZON-CL4-2025-04-DIGITAL-EMERGING-01: Advanced sensor technologies and multimodal sensor integration for multiple application domains (IA) (Photonics Partnership) | IA | 25 | 4 to 6 | 02/10/2025 |
| HORIZON-CL4-2025-04-DIGITAL-EMERGING-04: Assessment methodologies for General Purpose AI capabilities and risks (RIA) (AI/Data/Robotics Partnership) | RIA | 7 | 3 to 4 | 02/10/2025 |
| HORIZON-CL4-2025-04-DIGITAL-EMERGING-05: Soft Robotics for Advanced physical capabilities (IA) (AI/Data/Robotics Partnership) | IA | 20 | Around 10 | 02/10/2025 |
| HORIZON-CL4-2025-04-DIGITAL-EMERGING-06: Challenge-Driven GenAI4EU Booster (RIA) (AI/Data/Robotics Partnership) | RIA | 45 | Around 15 | 02/10/2025 |
| HORIZON-CL4-2025-04-DIGITAL-EMERGING-07: Enhanced Learning Strategies for General Purpose AI: Advancing GenAI4EU (RIA) (AI/Data/Robotics Partnership) | RIA | 30 | Around 15 | 02/10/2025 |
Destination 6: Digital and industrial technologies driving human-centric innovation
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60: Horizon Standardisation Booster (CSA) | CSA | 1.5 | Around 1.5 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61: Standardisation landscape analyses tool (CSA) | CSA | 1 | Around 1 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62: Artificial Intelligence for knowledge valorisation (CSA) | CSA | 2 | Around 2 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63: Value creation pilots for scaling up innovative solutions (CSA) | CSA | 2 | Around 2 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64: Pilot initiatives on Technology Infrastructures (CSA) | CSA | 5 | 0.5 to 1 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65: Network of Industry 5.0 system innovation hubs in connected Regional Innovation Valleys (IA) | IA | 3 | Around 3 | 23/09/2025 |
| HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66: Assessment of Technology Infrastructure needs in Ukraine (CSA) | CSA | 1.5 | 1 to 1.5 | 23/09/2025 |
| HORIZON-CL4-2025-03-HUMAN-14: Core technologies for virtual worlds (RIA) (Virtual Worlds and Photonics Partnerships) | RIA | 43 | 5 to 6 | 02/10/2025 |
| HORIZON-CL4-2025-03-HUMAN-15: GenAI4EU: Generative AI for Virtual Worlds – Advanced technologies for better performance and hyper-personalised and immersive experience (IA) (AI/Data/Robotics & Virtual Worlds Partnerships) | IA | 20 | 4 to 5 | 02/10/2025 |
| HORIZON-CL4-2025-03-HUMAN-16: Drive the evolution of the internet towards open and interoperable Web 4.0 and Virtual Worlds – building blocks in priority areas (RIA) (Virtual Worlds Partnership) | RIA | 14.5 | Around 3 | 02/10/2025 |
| HORIZON-CL4-2025-03-HUMAN-17: Specific support for the Virtual Worlds Partnership and the Web 4.0 initiative (CSA) (Virtual Worlds Partnership) | CSA | 2.5 | Around 2.5 | 02/10/2025 |
| HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub (CSA) (AI/Data/Robotics Partnership) | CSA | 3 | Around 3 | 02/10/2025 |
| HORIZON-CL4-2025-03-HUMAN-19: International cooperation in semiconductors (CSA) | CSA | 3 | Around 3 | 02/10/2025 |
| HORIZON-CL4-2025-04-HUMAN-08: GenAI for Africa | RIA | 5 | 1 to 2 | 02/10/2025 |
Destination 3: Developing an agile and secure single market and infrastructure for data- services and trustworthy artificial intelligence services
| Call topic | Type | Budget (EUR million) | Budget/ project | Deadline |
| HORIZON-CL4-2025-04-DATA-02: Empowering AI/generative AI along the Cognitive Computing continuum (RIA) (AI/Data/Robotics Partnership) | RIA | 30 | 6 to 8 | 02/10/2025 |
| HORIZON-CL4-2025-04-DATA-03: Software Engineering for AI and generative AI (RIA) (AI/Data/Robotics Partnership) | RIA | 15 | 4 to 6 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-08: Large-scale pilots for supply end-to-end infrastructures integrating device, network computing, and communication capabilities for Telco Edge Cloud deployments, as a basis for Connected Collaborative Computing Networks (3C networks) (RIA) | RIA | 75 | Around 75 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-09: Alignment of stakeholders towards the supply-side large-scale pilot of end-to-end infrastructures integrating device, network computing, and communication capabilities (CSA) | CSA | 2.5 | 1.8 to 2.5 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-10: Roadmap for next-generation computing technologies from IoT device level to edge to cloud to HPC (CSA) | CSA | 2.5 | 1.8 to 2.5 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-11: Open Internet Stack: development of technological commons/open-source 3C building blocks (RIA) | RIA | 10 | Around 10 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-12: Preparing the advancement of the state of the art of submarine cable infrastructures (CSA) | CSA | 2.1 | 1.9 to 2.1 | 02/10/2025 |
| HORIZON-CL4-2025-03-DATA-13: Fostering innovative and compliant data ecosystems (IA) (AI, Data and Robotics Partnership) | IA | 45 | 7 to 9 | 02/10/2025 |
* This information has been extracted from the draft Cluster 4 Work Programme available online. As its content is subject to change, accelopment cannot be held responsible for the content of this blog.
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Andreia Cruz
Research & Innovation Project Manager
Dr. Johannes Ripperger
Research & Innovation Manager