Testimonial The accelopment team knows what’s important for a successful EU proposal and how to competently manage it when funded.
Prof. Maria Vertzoni
Coordinator in AGePOP and PI in PEARRL and InPharma
National and Kapodistrian University of Athens, Greece

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AGePOP

Drug Absorption in Geriatric Patients and Older People: a training network innovating drug development for the advanced age population

The advanced age population (>65y) makes up ~20% of the total population in Europe, is the main carrier of chronic diseases and the major end-user group of medications. Yet, despite an ageing society, these end-users are entirely disregarded in the drug development process, which considers only healthy adults aged 18-55y. Effective absorption of oral drugs, which remain the preferred form of administration, relies on a sound knowledge of the physiological alterations associated with ageing and of the characteristics of the gastrointestinal (GI) tract in older subjects. Nonetheless, both the knowledge and the experts in this area are lacking.

The AGePOP European Training Network (ETN) will boost Europe’s innovation capacity and leadership in oral drug development. Its multisectoral approach will train 11 Early Stage Researchers (ESRs) to become the future experts in drug development for the advanced age population, shedding a much needed light on the needs of our ageing society. With an open science philosophy and a multidisciplinary strategy, the ESRs will collect the first ever dataset of physiological characteristics of the GI tract of older people and geriatric patients, developing novel in vitro and in silico tools, e.g. a mobile test kit to evaluate gastric emptying kinetics and an absorption risk calculator to predict adverse effects from altered pharmacokinetics. Complementary training in transferable, business and wider horizon skills will equip the ESRs with an all-rounded skillset. AGePOP is a network of 6 Beneficiaries and 7 Partner Organisations from 5 European countries. Its 3 academic partners with research excellence in oral drug products synergise with renowned clinicians and researchers from 8 leading pharma companies and 1 SME specialised in ETN training. Building on long-standing collaborations, the consortium will provide 11 ESRs with a unique Europe-wide learning experience, preparing them to lead their future careers with confidence and success.

Coordinator:
National and Kapodistrian University of Athens, GR

Partners:

Funded Project




AreaOther
ProgrammeFP7-SSH
Duration01.01.2009 - 31.12.2011
Budget1.9 million euro
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Training



We are happy to share our experience through transferable skills online training courses for ESRs in ongoing MSCA-ITNs. Pick and choose from six interactive, hands-on modules.

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Team



My passion for science and communication brought me from the lab to accelopment Switzerland, where I enjoy helping researchers transform ideas into concrete progress.

Dr. Emily Rose Ciscato
Project Manager Communications