Testimonial It is always a pleasure to work with the people from accelopment. In my experience they are dedicated, honest, and to the point.
Prof. Menno Prins
CONSENSE Project Coordinator
Technical University Eindhoven, Netherlands

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A game change in continuous biosensing: Molecularly engineered affinity-based nanoswitches for personal monitoring

Generic technology that allows continuous sensing of a wide range of biomolecular parameters could revolutionise patient monitoring and enable truly personalised therapy. Commercial sensors  are available for continuous monitoring of glucose, but do not exist for other molecules that are important for monitoring disease status and treatment effect, including peptides, proteins, hormones, and drugs. The ambition of CONSENSE is to provide a game change in continuous biomolecular sensing by combining advanced molecular engineering with tailored optical detection technologies to yield generic, affinity-based biosensing technologies.

CONSENSE will focus on the construction of biomolecular nanoswitches that translate molecular binding into robust and well-defined conformational changes at length scales that can be detected by selected optical detection methods, providing unique possibilities to distinguish between specific and nonspecific binding. While the applications for this new technology are wide and varied, within CONSENSE we will focus on immune monitoring in critical care settings, where patients have an urgent need for continuous monitoring related to inflammation and immunotherapy.

CONSENSE brings together internationally leading pioneers in biomolecular switch engineering with research groups that have an excellent track record in biosensor development using advanced optical approaches, including two high-tech companies that have spun out from these groups. The consortium is completed by a strong network of partner industries and organisations, including four large medical technology companies, clinical experts, and seven SMEs providing specific technological expertise and training. The consortium will provide exceptional training to 15 ESRs, allowing them to develop professionally and perform world-class research that will fundamentally advance the field of continuous biomolecular monitoring for healthcare.

This project contributes to the UN Sustainable Development Goals (SDGs) 3, 4 and 9.

Technische Universiteit Eindhoven, NL


Funded Project

Duration01.02.2016 – 31.01.2018
Budget0.27 million euro


There are endless opportunities out there to support research and development (R&D) in your company, the European Union alone supports 200 such programmes every year. In addition, there are numerous national programmes to support innovation activities in the private sector.



My main goal is to relieve the scientists of their workload so that they can fully concentrate on their projects, and with our support, tackle the challenges of the future.

Jacqueline Strehler
Research & Innovation Project Manager